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According to new research, a pain reliever used for low back pain may be associated with high risk of dementia and mild cognitive loss (MCI).
A study published online at the Journal Regional Anesthesia and Pen Medicine found that groups were considered very young to face risk twice while taking gabapantin.
The research team said in a press release, “Our findings indicate a connection between gabapantin prescription and dementia or cognitive loss,” the research team said.
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Researchers noted in a press release, the drug has become increasingly popular for the treatment of chronic pain, especially neuropathic (nerve) pain.
Gabapantin – According to the Cleveland Clinic, is also used to control seizures – there is relatively low addictive ability compared to traditional opioids.
Experts mentioned that Gabapantin has become increasingly popular for the treatment of chronic pain, especially neuropathic (nerve) pain, said experts. (Istock)
Recent research has given rise to new concerns on its side effects, including a possible relationship with neurodizonation.
The previous conclusions cannot confirm a specific link, especially whether some age groups are more weak.
In the latest study, researchers collected data from the trinatex, a health research network that recorded electronic health from 68 healthcare organizations across the US.
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While examining an anonymous records of adult patients, the team saw groups that were prescribed gabapantin for the lower back pain between 2004 and 2024 and compared to those who did not receive the drug. Each group had a total of 26,414 persons.
Researchers were responsible for factors such as demographics, co-existing conditions and other painkillers use.
People between 18 and 64 years old, who received gabapantin, were more than doubled to develop the situation than those who were not prescribed the drug. (Istock)
Patients who received six or more gabapantin tips were 29% more, which were likely to be diagnosed with dementia and were found to be diagnosed with 85% more MCI within 10 years of their initial pain diagnosis, found in the study.
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Given specific age groups, people aged 18 to 64 years older were more than double the possibility of developing the situation compared to those who were not determined by Gabapantin.
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While there was no risk between people between the ages of 18 and 34, who were prescribed the drug, the risk of dementia is more than doubled between 35 to 49 years of age (and the risk of MCI is more than three).
Researchers saw a similar pattern among children between 50 and 64 years old.
Patients who received six or more gabapantin tips were 29% more, which were likely to be diagnosed with dementia and were found to be diagnosed with 85% more MCI within 10 years of their initial pain diagnosis, found in the study. (Istock)
Risk with the frequency of leaflets increased: 12 or more tips patients had 40% more likely to develop dementia and was prone to 65% more MCI, which were determined by Gabapantin between three and 11 times.
“Our findings indicate a relationship between gabapantin prescription and dementia or cognitive loss within 10 years.”
The study had some limitations. Researchers stated that this was an observation study, as no firm conclusion could be extracted about the cause and impact.
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He also admitted that because the study was retrospective, they could not be responsible for the length of dosage or length of gabapantin.
Researchers stated that the results “support the need for close monitoring of gabapantine prescribed adult patients to assess for potential cognitive decline.”
